The International Medical Prevention Registry on Venous Thromboembolism (IMPROVE) (2001-2005) was a prospective cohort study of physician practices in the provision of prophylaxis against venous thromboembolism (VTE) in hospitalized medical patients. Key endpoints included type and duration of prophylaxis as well as death, clinically apparent VTE, and bleeding within 3 months of hospital discharge. This registry enrolled over 15,000 patients from 56 hospitals in 11 countries. The IMPROVE VTE risk score calculator and bleeding risk score calculator have been developed into multi-platform applications for use at the patient’s bedside. In particular, in December 2013 the IMPROVE bleeding risk score was selected by the Quality and Patient Safety Division (QPSD) of Commonwealth of Massachusetts Board of Registration in Medicine as the screening tool to improve VTE management. PDF

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